ntmscope_s
Molecular epidemiology of M. simiae complex
Introduction: Mycobacterium simiae is a slow-growing non-tuberculous mycobacterium that can cause non-tuberculous mycobacterium (NTM) pulmonary disease and extrapulmonary infections. Until now, detailed genomic and clinical characteristics, as well as possible transmission routes of this rare pathogen remain largely unknown. M. simiae is a member of the M. simiae complex that comprises M. genavense, M. lentiflavum and others.
Objectives: Investigation of the genomic populations of the M. simiae complex and the investigation of the longitudinal genomic stability within single patients colonised or infected with M. simiae.
Methods: Clinical and epidemiological data-analysis, whole genome sequencing, genotypic drug susceptibility testing.
Status: Data analysis completed
European Nucleotide Archive
Microreact project